Substrate: Cytokeratin 8 (keratin, type II cytoskeletal 8 (cytokeratin 8) (K8) (CK8) (from PhosphoBase))
Seq-ID: P05787 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-51056   RAF1_HUMAN
MINT-61555   GRB2_HUMAN
MINT-2984733   ZO1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural molecule activity,
protein binding		 cytoplasm,
keratin filament		 cytoskeleton organization,
interspecies interaction between organisms
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 21 KVSTSGPRAFSSRSYTSGPGS - 16083285
HTP
0.36
 - -
0.56
 - low
S 21 KVSTSGPRAFSSRSYTSGPGS - 18669648
HTP
0.36
 - -
0.56
 - low
S 22 VSTSGPRAFSSRSYTSGPGSR - 16083285
HTP
0.72
 - -
0.57
 - low
S 24 TSGPRAFSSRSYTSGPGSRIS - 16083285
HTP
0.92
 - -
0.58
 - low
S 24 TSGPRAFSSRSYTSGPGSRIS - 9054461
LTP
0.92
 - -
0.58
 - low
S 24 TSGPRAFSSRSYTSGPGSRIS - 18669648
HTP
0.92
 - -
0.58
 - low
Y 25 SGPRAFSSRSYTSGPGSRISS - 18669648
HTP
0.21
 - -
0.55
 - low
S 27 PRAFSSRSYTSGPGSRISSSS - 16964243
HTP
0.35
 - -
0.52
 - low
S 27 PRAFSSRSYTSGPGSRISSSS - 18669648
HTP
0.35
 - -
0.52
 - low
S 34 SYTSGPGSRISSSSFSRVGSS - 17081983
HTP
0.49
 - -
0.50
 - low
S 34 SYTSGPGSRISSSSFSRVGSS - 18669648
HTP
0.49
 - -
0.50
 - low
S 35 YTSGPGSRISSSSFSRVGSSN - 18669648
HTP
0.75
 - -
0.50
 - low
S 36 TSGPGSRISSSSFSRVGSSNF - 18669648
HTP
0.53
 - -
0.49
 - low
S 37 SGPGSRISSSSFSRVGSSNFR - 16083285
HTP
0.85
 - -
0.48
 - low
S 37 SGPGSRISSSSFSRVGSSNFR - 17081983
HTP
0.85
 - -
0.48
 - low
S 37 SGPGSRISSSSFSRVGSSNFR - 18669648
HTP
0.85
 - -
0.48
 - low
S 39 PGSRISSSSFSRVGSSNFRGG - 18669648
HTP
0.26
 - -
0.46
 - low
S 43 ISSSSFSRVGSSNFRGGLGGG - 16083285
HTP
0.37
 - -
0.40
 - low
S 43 ISSSSFSRVGSSNFRGGLGGG - 17081983
HTP
0.37
 - -
0.40
 - low
S 43 ISSSSFSRVGSSNFRGGLGGG - 18669648
HTP
0.37
 - -
0.40
 - low
S 74 TAVTVNQSLLSPLVLEVDPNI MAPK14 11788583
LTP
0.18
 MOD_ProDKin_1
 - -
0.28
 - low
S 74 TAVTVNQSLLSPLVLEVDPNI PKC_delta 15972820
LTP
0.18
 MOD_ProDKin_1
 - -
0.28
 - low
S 74 TAVTVNQSLLSPLVLEVDPNI MAPK8 11781324
LTP
0.18
 MOD_ProDKin_1
 - -
0.28
 - low
Y 204 VLIKKDVDEAYMNKVELESRL - 18083107
HTP
1.00
 - COIL
0.28
 - low
S 240 EEIRELQSQISDTSVVLSMDN - 18669648
HTP
0.66
 - COIL
0.42
 - low
S 243 RELQSQISDTSVVLSMDNSRS - 18669648
HTP
0.91
 - Filament
0.45
 - low
S 251 DTSVVLSMDNSRSLDMDSIIA - 18669648
HTP
0.54
 - Filament
0.36
 - low
S 253 SVVLSMDNSRSLDMDSIIAEV - 17081983
HTP
0.46
 - Filament
0.35
 - low
S 253 SVVLSMDNSRSLDMDSIIAEV - 18669648
HTP
0.46
 - Filament
0.35
 - low
S 258 MDNSRSLDMDSIIAEVKAQYE - 18669648
HTP
0.79
 - Filament
0.38
 - low
Y 267 DSIIAEVKAQYEDIANRSRAE - 18083107
HTP
1.00
 - Filament
0.39
 - low
S 274 KAQYEDIANRSRAEAESMYQI - 18669648
HTP
0.94
 - Filament
0.42
 - low
S 330 EIEGLKGQRASLEAAIADAEQ - 17081983
HTP
0.19
 - COIL
0.44
 - low
S 330 EIEGLKGQRASLEAAIADAEQ - 18669648
HTP
0.19
 - COIL
0.44
 - low
S 400 TYRKLLEGEESRLESGMQNMS - 18669648
HTP
0.51
 - Filament
0.50
 - low
S 410 SRLESGMQNMSIHTKTTSGYA - 18669648
HTP
0.34
 - -
0.59
 - low
S 424 KTTSGYAGGLSSAYGGLTSPG - 18669648
HTP
0.21
 - -
0.42
 - low
Y 427 SGYAGGLSSAYGGLTSPGLSY - 18669648
HTP
0.34
 - -
0.34
 - low
T 431 GGLSSAYGGLTSPGLSYSLGS - 18669648
HTP
0.12
 - -
0.30
 - low
S 432 GLSSAYGGLTSPGLSYSLGSS CDK1 9524113
LTP
0.40
 MOD_ProDKin_1
 - -
0.31
 - low
S 432 GLSSAYGGLTSPGLSYSLGSS MAPK3 9524113
LTP
0.40
 MOD_ProDKin_1
 - -
0.31
 - low
S 432 GLSSAYGGLTSPGLSYSLGSS CDK1 9054461
LTP
0.40
 MOD_ProDKin_1
 - -
0.31
 - low
S 432 GLSSAYGGLTSPGLSYSLGSS CDK1 9054461
LTP
0.40
 MOD_ProDKin_1
 - -
0.31
 - low
S 432 GLSSAYGGLTSPGLSYSLGSS - 18669648
HTP
0.40
 MOD_ProDKin_1
 - -
0.31
 - low
S 436 AYGGLTSPGLSYSLGSSFGSG - 18669648
HTP
0.29
 - -
0.34
 - low
Y 437 YGGLTSPGLSYSLGSSFGSGA - 18669648
HTP
0.13
 - -
0.36
 - low
S 438 GGLTSPGLSYSLGSSFGSGAG - 18669648
HTP
0.11
 - -
0.37
 - low
S 441 TSPGLSYSLGSSFGSGAGSSS - 18669648
HTP
0.28
 - -
0.38
 - low
S 442 SPGLSYSLGSSFGSGAGSSSF - 18669648
HTP
0.42
 - -
0.37
 - low
S 445 LSYSLGSSFGSGAGSSSFSRT - 18669648
HTP
0.23
 - -
0.39
 - low
S 451 SSFGSGAGSSSFSRTSSSRAV - 16565220
HTP
0.46
 - -
0.44
 - low
S 475 KIETRDGKLVSESSDVLPK   - 17081983
HTP
0.47
 - -
0.50
 - low
S 475 KIETRDGKLVSESSDVLPK   - 18669648
HTP
0.47
 - -
0.50
 - low
S 477 ETRDGKLVSESSDVLPK     - 18669648
HTP
0.63
 - -
0.52
 - low
S 478 TRDGKLVSESSDVLPK      - 18669648
HTP
0.66
 - -
0.51
 - low

Substrate: Cytokeratin 8 (keratin, type II cytoskeletal 8 (cytokeratin 8) (K8) (CK8) (from PhosphoBase))
Seq-ID: P11679 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural molecule activity,
protein binding		 sarcolemma,
keratin filament,
Z disc		 tumor necrosis factor-mediated signaling pathway,
cell morphogenesis involved in differentiation,
apoptosis,
response to other organism,
cell differentiation involved in embryonic placenta development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 21 KMSTSGPRAFSSRSFTSGPGA - 17242355
HTP
0.64
 - -
0.55
 - low
S 46 SSFSRVGSSSSSFRGSMGTGV - 17242355
HTP
0.07
 - -
0.44
 - low
S 47 SFSRVGSSSSSFRGSMGTGVG - 17242355
HTP
0.23
 - -
0.44
 - low
S 80 TAVTVNQSLLSPLKLEVDPNI - 16563375
LTP
0.18
 - -
0.33
 - low
S 80 TAVTVNQSLLSPLKLEVDPNI - 16818723
LTP
0.18
 - -
0.33
 - low
S 438 GLSSSYGGLTSPGFSYGMSSF - 16563375
LTP
0.39
 - -
0.37
 - low

Substrate: Cytokeratin 8 (keratin, type II cytoskeletal 8 (cytokeratin 8) (K8) (CK8) (from PhosphoBase))
Seq-ID: Q10758 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
structural molecule activity,
protein binding		 sarcolemma,
costamere,
keratin filament,
nuclear matrix,
nucleoplasm,
dystrophin-associated glycoprotein complex,
Z disc		 response to hydrostatic pressure,
sarcomere organization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 24 TSGPRAFSSRSFTSGPGARIS - 16396499
HTP
0.90
 - -
0.54
 - medium

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